000006: Plant Seed Specific Promoters
Case ID:
TEC2000-0006
Web Published:
7/21/2014
Description:
Constitutive promoters, such as the CaMV 35S
promoter, are commonly used for producing transgenic plants. However,
constitutive promoters offer very little expression control, and cause their
products to be expressed throughout the entire life of the plant and
ubiquitously in tissues of transgenic plants. This effect is often harmful to
the health of the plant, reducing bioreactor (plant) life and negatively
affecting the desired output. Tissue-specific promoters enable expression of
desired traits in targeted tissue only, and usually offer greater control of
expression timing and levels. Seed-specific promoters are a type of
tissue-specific promoters that provide these favorable characteristics for
expression control of seed products.
Description
This invention provides seed-specific promoters
that direct gene expression to plant seeds. The invention also reveals methods
for identifying seed-specific promoters, and methods for controlling gene
expression with novel seed specific promoters that limit expression to plant
seeds. The invention ultimately enables greater control of gene expression for
recombinant seed products, such as oils, in a manner that prevents expression of
the products in other tissues that may harm the plant.
Benefits
- Enables
greater expression control for genetically engineered seed products: The
promoters are active at various stages of seed development and enable control
of gene expression. Also, expression of targeted traits is directed to the
seed only, which prevents expression in other parts of the plant where the
trait could compromise the health of the plant.
Applications
The seed-specific promoters provided by this
invention are useful for controlling gene expression and optimizing the
production of genetically engineered seed products. The invention has the
potential to enable the genetic design of desirable traits e.g., seed oils
produced with specific fatty acid profiles. Potential applications include
vegetable oil production for food and energy purposes.
IP Protection
Status
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For Information, Contact:
Thomas Herlache
Assistant Director
Michigan State University - Test
517-355-2186
herlache@msu.edu
