090106: Sequence and Cloning of Methyl Butenol Synthase
Case ID:
TEC2009-0106
Web Published:
7/21/2014
Description:
There is a growing economic and environmental need for the development of
alternative fuel sources due to concerns of sustainability. An ideal biofuel
would be highly renewable, efficient as a fuel, inexpensive, and easy to produce
in high volume. A problem with many biofuels, including ethanol, is that they
can only be produced in certain locations and with volume-production
constraints. Methyl butenol, though, has the potential to be manufactured in
very large quantities, made almost anywhere, and will be relatively inexpensive
if it can be produced in a photosynthetic organism. Due to its chemical
structure, methyl butenol can be a gasoline alternative or a feedstock for
chemical synthesis.
Michigan State University’s technology relates to the identification and
cloning of the first genes encoding methyl butenol synthase and its use in
methyl butenol production through fermentation. The methyl butenol synthase gene
was isolated from several species of pine. Even though it was known that pine
trees naturally produce and release methyl butenol in the environment, the gene
useful for the enzymatic production of methyl butenol was not known until now.
Thus, this technology provides a practical method for producing methyl butenol
using methyl butenol synthase proteins and genes.
Benefits
· High yield alternative:
Methyl butenol
is a new biofuel that can be easily produced at high yield through microbial
fermentation.
·
High-volume and geographically flexible
production capacity: Microbial
fermentation can be scaled to provide large capacity and allow for production
almost anywhere local biofuel is being produced.
·
Lack of self-polymerization:
Methyl butenol doesn’t suffer from the
self-polymerization problem that is found in other fuel
alternatives.
·
Low production costs:
Compared to bioethanol, methyl
butenol production can be very inexpensive, especially if produced in a
photosynthetic organism that does not require a carbon-source
feedstock.
Applications
This
invention as applications as:
· New biofuel to replace
gasoline:
Fermentative organisms
carrying a methyl butenol synthase gene can produce methyl butenol as an
alternative to fossil fuels such as diesel and
gasoline.
·
New biofuel
additive: Methyl butenol can
replace ethanol or the previously phased out Methyl Tertiary Butyl Ether
(MTBE).
· New chemical feedstock:
This technology
could be combined with an isoprene production system to result in the chemical
synthesis of rubber.
IP
Protection Status
Patent
pending
Patent Information:
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Serial No. |
Patent No. |
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For Information, Contact:
Thomas Herlache
Assistant Director
Michigan State University - Test
517-355-2186
herlache@msu.edu