110050: A Novel Enzyme That Synthesizes Sesquiterpenes to Provide Insect Resistance in Plants
Case ID:
TEC2011-0050
Web Published:
7/21/2014
Description:
Zingiberene is a sesquiterpene produced by many plant species
including ginger, turmeric, cultivated tomato, and its wild relatives. It is
synthesized at particularly high levels in the trichomes of certain accessions
of the wild tomato species Solanum habrochaites and is a potent insect
repellent. The identification of a gene from S. habrochaites that
synthesizes zingiberene provides an opportunity to directly control the
synthesis of the chemical in other plant species to improve resistance to insect
pests.
Description
Michigan
State University’s technology is a novel enzyme from the wild tomato species
Solanum habrochaites that synthesizes a mixture of sesquiterpenes (C15
compounds). These volatile compounds (primarily zingiberene) are known to repel
insects. The proposed gene that synthesizes zingiberene gives the host plant
insect resistance. The gene provides resistance to whiteflies and thrips, which
are not controlled well by current Bt transgenic plant technology.
Benefits
·
Insecticide and insect repellent:
Zingiberene in conjunction with small concentration of assorted terpenes both
repels insects and kills any insect feeders.
·
Alternative synthesizing enzyme:
The proposed enzyme is capable of synthesizing zingiberene utilizing a gene from
S. habrochaites. Current natural sources of zingiberene are ginger and
turmeric root.
·
High product specificity:
Zingiberene is the primary product of the gene, constituting greater than 95
percent of the total sesquiterpenes produced by the enzyme.
Applications
·
Insect resistant crops
·
Supplements market
·
Flavors/fragrances
IP Protection
Status
Patent pending
Patent Information:
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For Information, Contact:
Thomas Herlache
Assistant Director
Michigan State University - Test
517-355-2186
herlache@msu.edu