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070081: Identification of the Gene for Amatoxin and Phallatoxin

Mushroom poisonings are not very common but they are difficult to diagnose. Amanita mushrooms produce multiple classes of toxins, the two most important being amatoxins and phallotoxins. Upon ingestion, amatoxin binds to the RNA polymerase II enzyme, effectively causing cytolysis of hepatocytes (liver cells). Phallotoxins destroy liver cells b...
Published: 7/21/2014   |   Inventor(s): Jonathan Walton, Heather Hallen, John ScotT-Craig, Hong Luo
Keywords(s): Actin, Amanitin, Mushroom poisoning, RNA polymerase Category(s): Biotechnology