040132: A Reactive Extrusion Process for Formation of Biodegradable, Bioabsorbable Co-Polymers of 1,4-Dioxan-2-one and a Cyclic Ester
Case ID:
TEC2004-0132
Web Published:
7/21/2014
Description:
Current methods for producing these polymers
typically result in low conversion of monomer to polymer product. Removal of the
monomer is a time and cost intensive procedure.
Description
This invention describes an approach to synthesize
copolymers of 1,4-dioxan-2-one and a cyclic ester using continuous extrusion and
an organometallic polymerization agent (catalyst or initiator) with good control
of conversion of monomer to polymer and of molecular weights.
Benefits
- High
efficiency: Continuous extrusion is a highly efficient method of
polymerization.
- Cost
effective: Lower costs due to high conversion of monomer to polymer,
eliminating monomer removal step. Bulk process eliminates the need for costly
solvents and solvent removal steps.
Applications
This invention produces copolymers which are
biodegradable and bioabsorbable. Primary uses of these polymers are in medical
applications such as orthopedic surgical repair, controlled release drug
delivery, wound closures, and as scaffolds for tissue growth. Major users of the
technology would be those companies that supply bioabsorbable polymers to the
medical use markets.
IP Protection
Status
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For Information, Contact:
Bradley Shaw
Technology Manager
Michigan State University - Test
517-355-2186
shawbr@msu.edu
