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080062: Adaptation of Human (Pro)renin Receptor for Drug Screening

The recent discovery of (pro)renin receptor, PRR, may have significant implications for intracellular signaling. Moreover, animal studies of PRR have shown that its gene knockout results in lifelessness. Thus, an understanding of PRR could lead to one or more valuable therapies. PRR is also involved in the regulation of blood pressure at a “localized”...
Published: 7/21/2014   |   Inventor(s): R. Michael Garavito, Dexin Sui, Yi Zheng
Keywords(s): ACE Inhibitors, Anti-Hypertension, Anti-Hypertensive Therapy, Prorenin, PRR, Renin Category(s): Medical, Biotechnology, Pharmaceutical