Search Results - rawle hollingsworth

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010008: A One-Step Synthesis of 5-Hydroxymethyl 2-Oxazolidinones

Oxazolidinones are a class of compounds containing 2-oxazolidone in the structure. They are used in chiral synthesis and are an important class of molecules in the pharmaceutical industry especially in the areas of antimicrobial and behavior disorder. Oxazolidinone based antimicrobials are especially active against some of the most resistant hu...
Published: 7/21/2014   |   Inventor(s): Rawle Hollingsworth, Guijun Wang
Keywords(s): Carbohydrates, Chirality, Oxazolidinone Category(s): Chemicals, Pharmaceutical

010007: A One-Step Route to Chiral 5-Trityloxymethyl Oxazolidinones

Oxazolidinones are a class of compounds containing 2-oxazolidone in the structure. They are used in chiral synthesis and are an important class of molecules in the pharmaceutical industry especially in the areas of antimicrobial and behavior disorder. Oxazolidinone based antimicrobials are especially active against some of the most resistant hu...
Published: 7/21/2014   |   Inventor(s): Rawle Hollingsworth, Guijun Wang
Keywords(s): Carbohydrates, Chirality, Oxazolidinone Category(s): Chemicals, Pharmaceutical

000073: Process and Intermediate Compounds for the Preparation of Pyrrolidines

Michigan State University’s invention relates to the preparation of pyrrolidines, preferably chiral, from tri-O-acetylketopentulosonic acid methyl esters. In particular, the invention relates to the preparation of 3,4-dihydroxy-5-hydroxymethyl pyrrolidines, which can be substituted or unsubstituted in the N position. IP Protection Status U....
Published: 7/21/2014   |   Inventor(s): Rawle Hollingsworth
Keywords(s):   Category(s): Biotechnology, Chemicals

000060: Process for the Preparation of a 1,5-Dideoxy-1, 5-Imino Hexitols from Oximes and Imines

Michigan State University’s invention relates to a multi-step synthesis of a 1, 5-dideoxy-1, 5-imino hexitol from a ketoaldonic acid methyl ester of a hexose sugar with protected hydroxyl groups to novel intermediates. In particular, the invention relates to processes which enable the production of novel intermediates to the hexitol and, in pa...
Published: 7/21/2014   |   Inventor(s): Rawle Hollingsworth, Gabriela PistiA-Brueggeman
Keywords(s):   Category(s): Biotechnology, Chemicals