Search Results - Test+and+Measurement

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Field-operable nuclear magnetic resonance (NMR)-based biosensor with embedded temperature control

Innovators at Michigan State University developed a portable Nuclear Magnetic Resonance (NMR)-based biosensor that utilizes magnetic nanoparticles as a biomarker for label-free isolation and detection of target bio-materials from complex sample matrices. The NMR-based biosensor operates at 0.47 Tesla, utilizing an embedded magnet and electrically-active...
Published: 7/30/2014   |   Inventor(s): Evangelyn Alocilja, Yilun Luo
Keywords(s):   Category(s): Medical, Biotechnology, Nanotechnology, Devices, Test and Measurement

080003: Noninvasive Neonatal Gastroesophageal Reflux Monitor

Some newborn infants have serious reflux problems that can result in gastric fluids ascending the esophagus to the trachea, where the fluid can then be aspirated into the lungs. Current gastroesophageal reflux (GER) diagnostic tests are invasive, use a pH probe mounted on a nasoesophageal catheter that does not detect non-acidic gastric reflux,...
Published: 7/21/2014   |   Inventor(s): Ira Gewolb, Frank Vice
Keywords(s): Accelerometer, Acoustic Device, Diagnostic Test, Gastroesophageal Reflux Disease (GERD), Low-Frequency Signal Processing Category(s): Medical, Test and Measurement

060077: Determining Ejection Fraction Volumes on a Continuous Basis

People with progressive heart failure need ejection fraction (EF) measurements as critical information in diagnosis and treatment. EF is the percentage of the total volume in a ventricular chamber of the heart that is ejected per beat, a key measure of overall heart function. A technology allowing continuous monitoring of EF would allow for much...
Published: 7/21/2014   |   Inventor(s): Ramakrishna Mukkamala
Keywords(s): Cardiac Output, Cardiovascular Disease, Ejection Fraction, Heart Monitoring, Left Ventricular Pressure, Software, Systemic Arterial Pressure, Waveform Analysis Category(s): Medical, Computer Software, Test and Measurement

950097: Computational Screeing and Docking Tool (SLIDE)

SLIDE (Screening for Ligands by Induced Fit Docking Efficiently) represents a general approach to organic and peptidyl database screening. It can handle large binding-site templates and uses multi-stage indexing to identify feasible subsets of template points for ligand docking. An optimization approach based on mean-field theory is applied to model...
Published: 7/21/2014   |   Inventor(s): Leslie Kuhn, Volker Schnecke, Paul Sanschagrin, Maria Zavodszky, Matthew Tonero
Keywords(s): Ligands, Protein Binding, Proteins, Screening Category(s): Medical, Test and Measurement

050010: Continuous Monitoring of Cardiac Output and Left Atrial Pressure

Cardiac output (CO) is the volume of blood ejected by the heart per unit time, while left atrial pressure (LAP) is the blood pressure in the left heart during the cardiac filling phase. Both CO and LAP permit the diagnosis of various cardiovascular disease processes and thereby facilitate imminent therapeutic decisions. Thus, the ability to monitor...
Published: 7/21/2014   |   Inventor(s): Ramakrishna Mukkamala, Richard Cohen
Keywords(s): Cardiac Output, Cardiovascular Disease, Heart Monitoring, Left Atrial Pressure, Pulmonary Artery Catheters, Pulmonary Artery Pressure, Right Ventricular Pressure, Waveform Analysis Category(s): Medical, Computer Software, Test and Measurement

040108: Method for the Separation of Peptide or Protein Materials

The recent focus on proteomics research has resulted in an increased demand for sophisticated methods to identify and analyze post-translational processing of proteins for the purpose of analyzing cellular signaling networks and diagnosing diseases. The reversible process of phosphorylation/dephosphorylation is one modification that is critical...
Published: 7/21/2014   |   Inventor(s): Jetze Tepe, Thomas Pinnavaia
Keywords(s): Phosphorylated Proteins and Peptides, Proteomics Category(s): Biotechnology, Pharmaceutical, Test and Measurement

040020: Engineering Functional Groups into Electrospun Nanofibers for Cell Culture

Cell culturing is the process of growing cells in an artificial environment under controlled conditions in an effort to cause the cells to behave as they would in vivo. This is difficult to achieve because, in addition to the conditions such as temperature, pH, and gas concentrations, nutrients and energy requirements must be supplied in cell culture...
Published: 7/21/2014   |   Inventor(s): Melvin Schindler, Hoo Chung
Keywords(s): Cell Culture, Cell Culture Additives, Nanofibrillar Surfaces, Sythetic Extracellular Matrix Category(s): Biotechnology, Test and Measurement, Pharmaceutical

000009: Anti-mycotoxin Compound and a Screening Test for Mycotoxin Inhibitors

Mycotoxins, metabolites produced by specific fungi, are introduced into the food chain by pre-harvest and post-harvest contamination of foods and livestock feed. Infestation of crops and food by mycotoxin producing fungi causes serious immunosuppressive, carcinogenic, cytotoxic, and teratogenic effects in humans and animals. The Aspergillus mycotoxin,...
Published: 7/21/2014   |   Inventor(s): Frances Trail, Ray Hammerschmidt, John Linz, Haixin Xu, Luis Velasquez, Seanna Annis
Keywords(s): Fungicide, Mycotoxin, Mycotoxin Transcription Inhibitors, Thin Layer Chromatography Category(s): Food Science and Nutrition, Test and Measurement, Agriculture