Search Results - jetze+tepe

3 Results Sort By:

040108: Method for the Separation of Peptide or Protein Materials

The recent focus on proteomics research has resulted in an increased demand for sophisticated methods to identify and analyze post-translational processing of proteins for the purpose of analyzing cellular signaling networks and diagnosing diseases. The reversible process of phosphorylation/dephosphorylation is one modification that is critical...
Published: 7/21/2014   |   Inventor(s): Jetze Tepe, Thomas Pinnavaia
Keywords(s): Phosphorylated Proteins and Peptides, Proteomics Category(s): Biotechnology, Pharmaceutical, Test and Measurement

030052: Preparation of Hymenialdisine Derivatives and potential Application to Treatment of Inflammatory Diseases, Alzheimer's, and Cancer

Cyclin-dependent kinases and NF-kB regulate a large number of genes and biochemical pathways. Deviations in their activity are associated with diseases, including those linked to immune, inflammatory, and anti-apoptotic responses. Many areas of drug discovery are focused on discovery of reagents that inhibit their activities. Naturally occurring...
Published: 7/21/2014   |   Inventor(s): Jetze Tepe
Keywords(s): Anti-inflammatory, Hymenialdisine, Indolazepine, Kinase Inhibitors, NF-kB Inhibitors Category(s): Medical, Biotechnology, Pharmaceutical

020060: Novel Multi-Substituted Imidazolines with Potential anti Microbial and Anti-inflammatory Application

NF-kB is a transcription factor that regulates a large number of genes and biochemical pathways, including those involved in immune, inflammatory, and anti-apoptotic responses. Many areas of drug discovery are focused on developing reagents that regulate NF-kB. Imidazolines are potent inhibitors of NF-kB, and are currently being used to treat a...
Published: 7/21/2014   |   Inventor(s): Jetze Tepe, Satyamaheshwar Peddibhotla
Keywords(s): Anti-inflammatory, Anti-microbial, Chemopotentiator, Imidazoline Category(s): Medical, Biotechnology, Pharmaceutical